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 1. Regulasi organ reproduksi jantan:  testis,  skrotum,  epididimis,  vas deferent,  uretra, dan  kelenjar asesoris  2. Struktur pendukung: 

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Presentasi berjudul: " 1. Regulasi organ reproduksi jantan:  testis,  skrotum,  epididimis,  vas deferent,  uretra, dan  kelenjar asesoris  2. Struktur pendukung: "— Transcript presentasi:

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2  1. Regulasi organ reproduksi jantan:  testis,  skrotum,  epididimis,  vas deferent,  uretra, dan  kelenjar asesoris  2. Struktur pendukung:  jaringan saraf dan  peredaran darah

3  Spermatogenesis  Hormonal control

4  Seminiferous tubules ◦ Spermatids ◦ Spermatocytes ◦ Spermatozoa ◦ Sertoli cells  Interstitial tissue ◦ Leydig cells ◦ Capillaries

5  Head ◦ Acrosome ◦ Nucleus  Midpiece ◦ Centrioles ◦ Mitochondria  Tail: flagellum ◦ Microtubules Figure 26-10: Sperm structure

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8 ◦ Nourish healthy cells & phagocytize damaged germ cells ◦ Synthesize luminal proteins ◦ Maintain tubular fluid ◦ Convert androgens to estrogens

9  BTB (in rats)  composed: ◦ tight junction ◦ basal ectoplasmic specialization ◦ basal tubulobulbar complex ◦ desmosome-like junction, at side-by-side in the seminiferous epithelium

10  Tight junctions sebagai tempat komunikasi antar sel TIGHT JUNCTION ANCHORING JUNCTION COMMUNICATING JUNCTION Plasma membranes of adjacent cells Extracellular matrix

11  The BTB physically  divides the seminiferous epithelium into basal and apical compartments  spermatogenesis  The function: ◦ Immunological barrier -cell antigens from the systemic circulation, ◦ Creates a microenvironment for germ-cell development

12  Spermatogenesis  the BTB to permit the preleptotene & leptotene spermatocytes (Late stage VII - VIII of the epithelial cycle)  BTB to facilitate germ-cell migration is regulated two cytokines to activated protein kinases: ◦ 1. Transforming Growth Factor-beta3 (TGF-beta3) ◦ 2. tumor necrosis factor-alpha (TNFalpha)

13  Terletak di antara seminiferous tubules  Di jumpai banyak kapiler darah dan populasi sel somatik lainnya  Menghasilkan hormone testosteron (Franz von Leydig, , German)  Bentuk: cuboidal & in groups of 2-20 cells  Testosteron menstimuli perkembangan sek sekunder jantan (rambut & bentuk tubuh)  The pituitary hormone ICSH (Interstitial Cell Stimulating Hormone) menstimuli produksi testosteron saat puber

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15  Rete Testis ◦ channels lined with a low cuboidal epithelium, like channels in a river delta  Efferent ducts ◦ The efferent ducts (7-15 seminiferous tubules )  Epididymis ◦ Long & extremely coiled single duct ◦ Extra testicular organ  Ductus Deferens ◦ relatively short & highly coiled ducts ◦ pseudostratified columnar epithelium

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19  Prostate gland ◦ radially around the urethra (upper right) ◦ 20% total volume semen  Seminal Vesicle ◦ 60 % total volume semen  Bulbourethral gland (Cowper gland)  Ejaculat ◦ pH 7,2-8,2

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21 Tersusun atas: 1.Korpus spongiosum: terletak disekitar uretra, penuh kapiler darah 2.Korpus cavernosum: terletak di bagian dorsal, terdapat pembuluh darah besar

22 Sintesis protein di epididymis: tergantung konsentrasi androgen dan kepekatan cairan Sintesis hormon steroid: 5-alpha dihydroxytestosterone (DHT), disekresikan di sitoplasma bagian caput, corpus, & cauda Secretion of epididymal segments → epithelium epididymal In rats, the proximal & in the distal epididymis → * the proximal epididymis → 27 & 29-kD * the distal epididymis → kD

23 TERIMA KASIH ATAS PERHATIANNYA


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