Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek: pharmacon (poison) epi (concerning)

Presentasi berjudul: "Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek: pharmacon (poison) epi (concerning)"— Transcript presentasi:

1 Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek: pharmacon (poison) epi (concerning) demos (people) logos (study)

2 DEFINISI FARMAKOEPIDEMIOLOGI
“Farmako” dan “Epidemiologi” Farmakologi: studi mengenai efek tentang obat Farmakologi klinik: studi tentang efek obat pada manusia  farmakokinetik dan farmakodinamik Epidemiologi: studi mengenai distribusi dan penyebab penyakit pada populasi tertentu

3 DEFINISI FARMAKOEPIDEMIOLOGI
Jadi, farmakoepidemiologi merupakan: Ilmu terapan yang menjembatani antara farmakologi klinik dan epidemiologi Penerapan metode epidemiologi pada ilmu farmakologi klinik

4 Pharmacoepidemiology
In epidemiology, primary focus is the relationship between exposure to a risk factor and disease outcome. In pharmacoepidemiology, the exposure is the drug and the outcome is an adverse drug reaction. Hence in many ways, pharmacoepidemiology is a subset of epidemiology and uses epidemiological methods

5 “The study of the use and effects of medications in large numbers of people”
Strom

6 “The application of epidemiologic knowledge, methods, and reasoning to the study of the effects (beneficial and adverse) and use of drugs in human populations.” Porta and Hartzema

7 “The study of drugs as determinants of health and disease in the general unselected population.”
Spitzer

8 Clinical pharmacology Pharmacoepidemiology
Strom

9 Pharmacoepidemiology
Pharmacology Therapeutics Pharmacoepidemiology Epidemiology Statistics Spitzer

10 Conceptualization by Harry Guess
Health services research Economics Epidemiology Health economics Outcomes research Clinical epidemiology Pharmaco- Epidemiology Conceptualization by Harry Guess

11 AREAS Pharmacoepidemiology has four major areas:
• Benefit: obtained from efficacy and effectiveness • Safety: obtained by pharmacovigilance • Use: obtained by drug utilization review • Value: obtained by pharmacoeconomics