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Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek:   pharmacon (poison)   epi (concerning)

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Presentasi berjudul: "Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek:   pharmacon (poison)   epi (concerning)"— Transcript presentasi:

1 Definisi Medical science applied to interactions between marketed medications and the population Comes from Greek:   pharmacon (poison)   epi (concerning)   demos (people)   logos (study)

2 DEFINISI FARMAKOEPIDEMIOLOGI “Farmako” dan “Epidemiologi” Farmakologi: studi mengenai efek tentang obat Farmakologi klinik: studi tentang efek obat pada manusia  farmakokinetik dan farmakodinamik Epidemiologi: studi mengenai distribusi dan penyebab penyakit pada populasi tertentu

3 Jadi, farmakoepidemiologi merupakan: Ilmu terapan yang menjembatani antara farmakologi klinik dan epidemiologi Penerapan metode epidemiologi pada ilmu farmakologi klinik DEFINISI FARMAKOEPIDEMIOLOGI

4 Pharmacoepidemiology In epidemiology, primary focus is the relationship between exposure to a risk factor and disease outcome. In pharmacoepidemiology, the exposure is the drug and the outcome is an adverse drug reaction. Hence in many ways, pharmacoepidemiology is a subset of epidemiology and uses epidemiological methods

5 “The study of the use and effects of medications in large numbers of people” Strom

6 “The application of epidemiologic knowledge, methods, and reasoning to the study of the effects (beneficial and adverse) and use of drugs in human populations.” Porta and Hartzema

7 “The study of drugs as determinants of health and disease in the general unselected population.” Spitzer

8 Pharmacoepidemiology Clinical pharmacology Epidemiology Strom

9 Pharmacoepidemiology Pharmacology Epidemiology Therapeutics Statistics Spitzer

10 Health services research Clinical epidemiology Health economics Outcomes research Pharmaco- Epidemiology Economics Conceptualization by Harry Guess

11 AREAS Pharmacoepidemiology has four major areas: Benefit: obtained from efficacy and effectiveness Safety: obtained by pharmacovigilance Use: obtained by drug utilization review Value: obtained by pharmacoeconomics


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