Pemanfaatan prinsip-prinsip dan kerekayasaan terhadap organisme, sistem atau proses biologis untuk menghasilkan atau meningkatkan potensi organisme maupun menghasilkan produk dan jasa bagi kepentingan hidup manusia HystoryDevelopingImplication Advantages disadvantages GGenetic Engineering Cloning Mikrobiologi Biologi sel Genetika Biokimia

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 8000 SM: Pengumpulan benih untuk ditanam kembali, praktik pengembangbiakan selektif SM: Pembuatan bir, fermentasi anggur, pembuatan roti dengan bantuan ragi 4000 SM: Yogurt dan keju dengan bakteri asam laktat 1500 : Collecting all plants in the world 1665: Cell invention by Robert Hooke 1800: Nikolai I. Vavilov create comprehension research about animal development 1880: Microorganisme invention 1856: Early recombinan of plant genetic by Gregor Mendel 1928: Penemuan Penicilin oleh Alexander Flemming 1970: Penemuan enzim pemotong gen oleh ilmuan AS 1975: Metode produksi monoclonal antibody oleh Kehler dan Milstein 1978: Made insulin from colon bacterial 1980: DNA recombinan technology 1992: FDA menyetujui makanan flavour saver tomato 2000: Perampungan Human Genom Project Sejarah Perkembangan Bioteknologi

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning Traditional Modern Traditional vs Modern Biotechnology Minuman anggur dan roti hasil bioteknologi tradisional. Tanaman kapas tahan hama hasil rekayasa genetika.

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 1.Food and Plants Production Developing Biotecnology Nata de Coco Tapai, tempe, keju Rhizobium leguminosarum

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 2.Organic Acids, Solvent and Biomass Production in Non- Steril Condition Developing Biotecnology Etanol Pengolahan limbah Bakteri asam laktat

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 3. Steril Condition Process Developing Biotecnology Penicilin dari Penicillium notatum Vitamin B12 dari Crysonilia sitophila

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 4.New Result Application of Scientific Knowledge Developing Biotecnology Hormon insulin dari E. coli

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 1.Foodstuff Producer and Changing Agents Use of Microorganism yoghurt dengan Lactobacillus. (a) Oncom dan (b) jamur oncom Neurospora SCP dari chlorella

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 2.Producing Medicine Use of Microorganism Antibiotik Streptomyces griseus : streptomisin Streptomyces venezuele : kloramfenikol Penecilin, klorotetrasiklin Vaksin

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 3. Bioinsecticide Use of Microorganism Pengaruh spora dan toksin Bacillus thuringiensis terhadap hama ulat. Trichoderma, bio fungisida (melawan Sclerotium)

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 4. Treatment of Waste and Polutants Use of Microorganism Clostridium butyrium, methanobacterium, Pseudomonas

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 5. Mining Use of Microorganism Theobacillus ferro-oxidans

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 1.Plant 1.Animal Cloning Tissue Culture

Hystory Developing Implication Advantages disadvantages GGenetic Engineering Cloning 2. Animal Cloning

Learning Objectives: After learn in this sesion, you must be able to: 1.Menjelaskan pengertian rekayasa genetika. 2.Menjelaskan 2 teknik yang digunakan dalam proses rekayasa genetika. 3.Menguraikan proses rekayasa genetika yang menggunakan teknik hibridoma (pembuatan antibodi monoklonal). 4.Menguraikan 2 proses rekayasa genetika yang menggunakan teknik plasmid/DNA rekombinan (pembuatan insulin). Genetic Engineering

Banana vaccines Venomous cabbage Glow-in-the-dark cats Super carbon-capturing plants

1.Teknik hibridoma dan plasmid rekayasa genetika teknik plasmid/DNA rekombinan pembuatan insulin teknik hibridoma antibodi monoklonal Genetic Engineering

1.Teknik hibridoma dan plasmid/DNA rekombinan Genetic Engineering Tahapan dasar Contoh : pembuatan insulinpembuatan insulin Pembuatan antibodi monoklonal Pembuatan antibodi monoklonal